In Vitro Disease Modeling & Cell Engineering

Development and use of engineered biological systems, such as organ-on-a-chip devices, dynamic hydrogels, or genetically modified cells, to mimic physiological conditions, study disease mechanisms, screen compounds, or develop cell-based therapies.

4,246 US filings from 1,928 companies since 2023 · 2023: 1,022 · 2024: 1,354 · 2025: 1,275 · 2026 YTD: 595

Material & Chemical Analysis

Top companies

Ranked by filings in this theme since 2023. 2026 is partial.

#	Company	Since 2023	2023	2024	2025	2026 YTD	YoY
1	The Regents of the University of California	107	32	33	28	14	-15.2%
2	President and Fellows of Harvard College	91	22	37	24	8	-35.1%
3	Wisconsin Alumni Research Foundation	54	18	14	14	8	0.0%
4	Vertex Pharmaceuticals Incorporated	44	4	21	13	6	-38.1%
5	The Trustees of Columbia University in the City of New York	40	3	14	11	12	-21.4%
6	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	40	9	13	15	3	+15.4%
7	The Board of Trustees of the Leland Stanford Junior University	38	12	9	12	5	+33.3%
8	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	37	15	13	6	3	-53.8%
9	CEDARS-SINAI MEDICAL CENTER	36	9	14	9	4	-35.7%
10	The General Hospital Corporation	35	7	14	12	2	-14.3%
11	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE	34	5	9	11	9	+22.2%
12	EMULATE, INC.	34	11	20	3	·	-85.0%
13	BOE Technology Group Co., Ltd.	31	8	9	12	2	+33.3%
14	Regeneron Pharmaceuticals, Inc.	30	5	10	13	2	+30.0%
15	The Johns Hopkins University	30	4	8	13	5	+62.5%
16	Children's Hospital Medical Center	28	3	4	12	9	+200.0%
17	UNIVERSITY OF WASHINGTON	26	4	8	12	2	+50.0%
18	GEORGIA TECH RESEARCH CORPORATION	23	7	9	5	2	-44.4%
19	INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)	23	7	8	7	1	-12.5%
20	Kyoto University	22	3	10	4	5	-60.0%
21	Osaka University	22	3	9	8	2	-11.1%
22	Yale University	22	3	7	11	1	+57.1%
23	CORNELL UNIVERSITY	21	3	4	11	3	+175.0%
24	Board of Regents, The University of Texas System	20	4	7	7	2	0.0%
25	Duke University	20	6	9	3	2	-66.7%